About
The American Association for Scientist Entrepreneurship (AASE) is a global organization dedicated to advancing science-driven entrepreneurship. While many institutions focus on supporting innovation, AASE takes a fundamentally different approach: we seek to understand, define, and systematize why some scientists succeed in entrepreneurship while others do not.
Scientific discovery alone does not guarantee impact. Across biotechnology, artificial intelligence, and deep-tech fields, only a small fraction of research breakthroughs are translated into real-world applications. This gap is not random—it reflects underlying patterns, structural constraints, and misalignments between science, capital, and market systems. AASE was established to address this challenge at its root. We are building a new field of study—scientist entrepreneurship—that examines the full lifecycle of innovation, from laboratory discovery to global impact. Through rigorous research, data analysis, and real-world case studies, we identify the key factors that determine success and failure in science-driven ventures.
Our work spans multiple dimensions. We study scientists across disciplines, geographies, career stages, and backgrounds. We analyze how differences in training, personality, ecosystem, and access to capital influence entrepreneurial outcomes. We examine both successful ventures and failed attempts to uncover repeatable patterns and actionable insights. At the core of AASE is the belief that scientist entrepreneurship is not an art—it is a system. By developing theoretical frameworks, data-driven models, and evidence-based strategies, we aim to transform entrepreneurship from a trial-and-error process into a structured, predictable pathway.
AASE operates through its research institute, global network, and academic initiatives, including the AASE Journal. We engage scientists, entrepreneurs, investors, and policymakers in a shared effort to improve the efficiency of innovation translation. Our goal is not only to support individual founders, but to shape the broader ecosystem in which science-driven enterprises emerge and grow.
Ultimately, AASE is not just an organization—it is a platform for defining the future of innovation. We do not just study how scientists innovate. We define how scientists succeed or fail in entrepreneurship.
We believe that scientific research can not only change the world, but also create value.
Our Mission
Our mission is to advance science-driven entrepreneurship by uncovering the fundamental principles that govern success and failure in the translation of scientific discovery. We aim to build a rigorous, data-informed understanding of how research becomes real-world impact, and to transform this understanding into actionable frameworks for scientists, institutions, investors, and policymakers. Through research, education, and global collaboration, AASE seeks to accelerate the transition from laboratory discovery to societal application. By aligning science, capital, and strategy, we empower scientists to become effective innovators and leaders, while contributing to the development of a more efficient, inclusive, and impactful global innovation ecosystem.
Our Vision
Our vision is to establish AASE as the world’s leading authority on scientist entrepreneurship, defining global standards for how scientific discoveries are translated into innovation. We aim to shape a future in which the success of science-driven ventures is no longer uncertain, but guided by clear principles, structured pathways, and measurable outcomes.
Our Board Members
(President, Vice President, Secretary, Treasurer, Board Member(s))
 Board Member of AASE |  Treasurer of AASE |  Secretary of AASE |  Vice President of AASE |
|---|---|---|---|
 Jack (Jie) Huang MD, PhDPresident of AASE |